Metabolic Phenotyping Core

Human based nutrition and obesity research studies are generating data at an unparalleled pace. These data permit investigators to generate many disease-related hypotheses; however the sophisticated infrastructure needed to create disease-relevant models and the detailed metabolic technologies necessary to test these hypotheses lie outside the expertise of many individual research groups. Core Director Alex Soukas’s recent work in Cell, describing two metformin response elements, conserved from worms to humans, through which metformin inhibits cancer growth and prolongs lifespan exemplifies the type of translational work supported by this Core.

The goal of the Metabolic Phenotyping Core is to provide users with access to high-quality model creation and detailed metabolic phenotyping.

Primary Contact: Alex Soukas

Core Leadership


soukasAlexander Soukas, MD, PhD
Co-Director of Metabolic Phenotyping Core
Assistant Professor of Medicine
Massachusetts General Hospital, Center for Human Genetic Research
CPZN6224, 185 Cambridge St.
Boston, MA  02114


Robert Gerszten
Co-Director of Metabolic Phenotyping Core
Herman Dana Professor of Medicine
Beth Israel Deaconess Medical Center
330 Brookline Ave.
Boston, MA  02215
Phone: 617-661-7000



Research utilizing the services of this core should please cite grant P30 DK040561 in any publications.